Methylene Blue Gummies Review 2026: 8 Brands, COAs Audited

By NooBlue Editorial · About our editorial standards · 8 brands compared

Short answer: NooBlue Methylene Blue Gummies are our pick in this methylene blue gummies review. Each gummy gives a stated 10 mg of methylene blue with 25 mg of vitamin C, the label shows 0 g sugar, and the product page links the lab report for the methylene blue ingredient lot. MaxLife Naturals costs less per milligram, and TrueHealthic shows a certificate that names its finished gummy, though its lot details need a closer look.

This review covers eight methylene blue gummies you can buy in 2026. NooBlue makes methylene blue gummies, capsules and drops. Our gummy is our pick, and every figure for the other seven brands comes from their own product pages or Amazon listings, read in September 2026. We did not lab-test any competitor product. We did open every certificate of analysis the brands show on their product pages and read what each one covers, which is where the gummies differ most. For a wider field that includes troches and bars, see our comparison of the best methylene blue gummies. If the format is new to you, start with what methylene blue gummies are.

Methylene Blue Gummies Review 2026: The 8 Brands Compared

The table puts every gummy on the same footing: price per gummy and price per milligram of methylene blue, so a 5 mg gummy and a 12 mg gummy can be compared fairly. One gummy is one serving on every label here except Blissta, whose serving is two gummies. Prices are as of Sep 2026 and move often, especially on Amazon.

Two patterns stand out. The gummies that cost least per milligram show no lab document at all. And the three documents that do exist answer different questions, so “has a COA” on its own tells you very little. The next section reads each one.

What the Certificates Actually Show: Our COA Audit

A certificate of analysis (COA) is a lab’s report on one sample. Three questions decide what it is worth to you. What was tested: the raw methylene blue, or a finished gummy, and which lot? What was measured: identity, purity, milligrams per gummy, heavy metals, microbes? And does it match the product in your cart? Our guide to reading a methylene blue certificate of analysis walks through each line, and our explainer on what 99% USP purity means covers the purity claims you will see on these labels.

The TrueHealthic finding needs care. The certificate on the gummy page names “TrueHealthic Methylene Blue Gummies” as the sample, received October 29, 2025. The ClearCert certificate shown with TrueHealthic’s own 1% drops carries the same Lab ID (24003), the same lot number (MB2402-BL30) and the same four metal results, but names the sample “Methylene Blue 1% Solution – 30mL Bottle”, received February 19, 2024 and reported May 1, 2025. A gummy and a liquid should not share one lot number and identical results. There may be a simple explanation, such as a reused template, but the documents alone do not tell you which product the numbers belong to. If you are weighing TrueHealthic, ask the brand for the lab’s original report for your lot.

Blue Organics shows a real lab report, for a different thing. The only document on the gummy page is a January 2024 heavy-metal and microbe screen of a methylene blue powder. It includes no test of identity or purity, and nothing links it to the gummies you would receive. The page banner still says “Every batch third-party tested – certificate published”.

Our own certificate has limits too. It covers the methylene blue ingredient lot, not a finished bottle of gummies. It confirms identity by HPLC and reports four heavy metals, and it gives no purity percentage. The product page says the same thing in plain words and links the full document, so you can check the lot number yourself. TrueHealthic’s certificate names a finished gummy, which ours does not.

The 8 Methylene Blue Gummies, Ranked

1. NooBlue Methylene Blue Gummies: our pick

What you get. 60 gummies per bottle, one gummy per serving. Each gummy has 10 mg of methylene blue (as methylene blue USP) and 25 mg of vitamin C, with 6 calories and 0 g total sugars. The rest of the chew is pectin, blueberry extract, stevia extract, sodium citrate and citric acid, in a Wild Blueberry flavor. The label says to chew one gummy daily, so a bottle is a 60-day supply.

Price. $49.99 a bottle, which is $0.83 a gummy and $0.083 per milligram of methylene blue. Two bottles are $89.98 and five are $199.96, which brings the cost to $0.067 per milligram.

Why it is our pick. The dose is printed per gummy, so there is no guessing and no measuring. The gummy pairs methylene blue with vitamin C, which can donate electrons to methylene blue and shift it toward its colorless form. NooBlue gummies don’t leave the blue mouth or tongue that liquid drops can, and the deep purple color comes from blueberry extract. The ingredient certificate is linked from the product page with its lot number, and the page lists the full safety warnings, including G6PD deficiency.

What to weigh. It is not the cheapest per milligram: MaxLife and Holistic MD cost less when their Amazon offers are live. The certificate covers the ingredient lot, not the finished gummy. And 10 mg is a fixed step. If you want to start lower, our 5 mg methylene blue capsules give a smaller fixed dose, and the 1% methylene blue drops give 0.5 mg per drop. Our guide to how many mg of methylene blue per day covers how people choose a daily amount.

See NooBlue Methylene Blue Gummies

2. MaxLife Naturals Liposomal Pure Methylene Blue Gummies: lowest cost per milligram

The MaxLife Naturals Amazon listing sells 60 gummies at 12 mg each for $24.98, or $0.42 a gummy. That is $0.035 per milligram, the lowest in this review. The title lists vitamin C ester, NAC and glycine alongside the methylene blue, in a raspberry flavor.

The brand’s own store is less clear. There the same 60-count gummy is $39.98, the page does not state milligrams per gummy (“Take as directed on the label”), and it promises “Every batch tested for purity and potency” and a 60-day money-back guarantee without showing a certificate. We found no warning about serotonergic medicines or pregnancy on the store page. “Liposomal” is also doing a lot of work here: neither page gives any detail on the liposome or any absorption data for this gummy.

Best for: buyers who want the most methylene blue per dollar and are comfortable with extra actives and no lab document.

3. Holistic MD Methylene Blue Gummies: lowest price per gummy, when an offer is live

The Holistic MD Amazon listing describes 60 sugar-free, vegan, gelatin-free gummies with a “7mg and 14mg daily dose” in a blueberry and blackberry flavor. Read with the 60-serving count, that points to 7 mg per gummy and two gummies for 14 mg. The title says “USP Pharma Grade” while the bullets say “USP Food Quality”, and “3rd Party Certified” appears with no lab, lot or document named.

When we checked, the listing had no featured offer. An Amazon carousel showed one seller offer from $23.95, which works out to $0.40 a gummy and $0.057 per milligram. That offer may not be there when you look. Our Holistic MD methylene blue gummies review covers the listing in more depth.

Best for: sugar-free buyers who want a 7 mg step and can find a live offer.

4. Blissta Ultra Blue Gummies: a two-gummy 14 mg serving

The Blissta Ultra Blue Gummies page sells a 60-gummy pouch for $39.99, described as a 30-day supply at two gummies a day. The page gives “14mg per 2-gummy serving”, so each gummy holds 7 mg. That is $0.67 a gummy, $1.33 a serving and $0.095 per milligram. It is sugar free and adds vitamin C.

The label figures don’t agree with each other. One section lists vitamin C at 11 mg per serving and another at 20 mg per serving, and the product’s own web address says 15 mg. The page says “Every lot is third-party tested and the Certificate of Analysis is published”, but we found no certificate or link to one on the product page. The warnings cover serotonergic medicines, pregnancy, breastfeeding and under-18s. We found no G6PD line.

Best for: buyers who like a two-gummy routine and will ask for the certificate before ordering.

5. Inditropic Methylene Blue Gummies: lowest pack price

The Inditropic Amazon listing sells 30 gummies at 5 mg each for $19.99, the lowest pack price in this review. That is $0.67 a gummy and $0.13 per milligram. The title claims “99.9% Pure”, the ingredients field lists vitamin C, and the brand field reads MCArthur.

The listing describes no testing and shows no document, and its title leans on outcome promises rather than label detail. A 30-count pack is a small commitment if you only want to try the format. Our Inditropic methylene blue review compares it with other 5 mg gummies.

Best for: a low-cost first try of a 5 mg gummy, accepting no lab proof.

6. TrueHealthic Methylene Blue Gummies: a certificate that names the finished gummy

The TrueHealthic gummy page sells 30 gummies at 5 mg each for $29.99, against a listed compare-at price of $80. That is $1.00 a gummy and $0.20 per milligram. The page claims “USP-Grade 99.9% Pure” and “3rd Party Tested”, and its text lists no other ingredients.

TrueHealthic is the only brand here whose document names a finished gummy as the sample, and that deserves credit. The lot-number overlap with its drops certificate, set out in the audit above, is the reason it sits lower than its paperwork alone would suggest. The page’s FAQ tells people on SSRIs, SNRIs, MAO inhibitors or other antidepressants to consult their doctor, rather than not to take it, and we found no G6PD or pregnancy warning on the page. Our TrueHealthic methylene blue gummies review has more detail.

Best for: buyers who want a certificate naming the gummy, once the brand confirms which lot it belongs to.

7. Blue Organics Methylene Blue Gummies: 5 mg with a raw-powder lab report

The Blue Organics gummy page sells a 30-gummy pouch for $36.00 (compare-at $55). Each gummy has 5 mg of methylene blue trihydrate, so it is $1.20 a gummy and $0.24 per milligram, the most expensive stated dose here. The other ingredients are cane sugar, glucose syrup, pectin, citric acid, natural flavor and purified water, so this is not a sugar-free gummy.

The page does carry a clear safety advisory: adults only, not during pregnancy or nursing, and not with prescription medicines, especially SSRIs, MAOIs or other serotonergic drugs. Its lab document is the 2024 powder report described above.

Best for: buyers who want a sugar-based 5 mg chew and a brand that shows at least some lab paperwork.

8. Neuropoise Methylene Blue Gummies: single-ingredient formula, dose not stated

The Neuropoise gummy page sells 30 blueberry gummies per pouch for $29.95 (compare-at $39.95), or $1.00 a gummy. The description reads “USP-Grade, 99.9% pure Methylene Blue”, non-GMO, alcohol free and “3rd party tested”, and the FAQ says to take one gummy daily. We could not find a milligram figure per gummy anywhere on the page, so price per milligram cannot be worked out.

A spare formula with no blends is a fair selling point. But the dose is the most important number on a methylene blue label, and without it you cannot compare value or plan a daily amount. The page has a general “consult your healthcare provider” note and no named warning about serotonergic medicines that we could find.

Best for: buyers who want a single-ingredient gummy and will ask the brand for the dose first.

Does the Leuco Form Matter?

Methylene blue is a redox dye. In its oxidized state it is the vivid blue compound that stains. When it accepts electrons it becomes leucomethylene blue, which is colorless. The two are halves of one reversible cycle, not two different ingredients.

That cycle is why researchers study methylene blue for mitochondrial energy. In a 2008 study in cultured human IMR90 fibroblasts, nanomolar methylene blue raised mitochondrial complex IV activity by 30% and cellular oxygen consumption by 37% to 70%. The authors describe cell enzymes using NAD(P)H to reduce methylene blue to its leuco form, and cytochrome c turning it back (Atamna et al., FASEB Journal). These were cells in a dish, not people, so read them as mechanism, not as a result you will feel.

Vitamin C can donate electrons to methylene blue, which is why several gummies here include it: NooBlue, Blissta, Inditropic and MaxLife all list vitamin C. No brand in this review publishes a measured split between the oxidized and leuco forms in its finished gummy, NooBlue included, and no study we found compares how well the two forms are absorbed in people. So be wary of any label that quotes an absorption multiplier. What you can check is simpler: whether the dose is stated, and whether the gummy leaves your mouth blue. For more on how chews are built, see what goes into a methylene blue gummy.

Do Methylene Blue Gummies Really Work?

No trial has tested any methylene blue gummy, ours included. The best human evidence comes from a randomized, double-blind, placebo-controlled imaging study at the University of Texas. It enrolled 26 adults aged 22 to 62. The 13 in the methylene blue group took a single 280 mg oral dose, about 4 mg/kg, and one hour later showed about a 7% increase in correct memory-retrieval responses along with changes in brain activity during attention and memory tasks (Rodriguez et al., Radiology, 2016). A second paper from the same group reported changes in functional connectivity (Rodriguez et al., Brain Imaging and Behavior, 2017).

That was one dose, 28 times a 10 mg gummy, in a small group. It supports the idea that methylene blue can support brain energy metabolism, which reviews such as Rojas and colleagues (2012) describe in detail. It does not show what a daily 5 to 12 mg gummy does over weeks. Our look at whether methylene blue gummies are effective goes further into the gap between the studies and the products.

Why Don’t Doctors Recommend Methylene Blue?

Many doctors know methylene blue as an injectable hospital medicine, used at far higher doses than any gummy. Their caution about supplements comes mostly from interactions. Methylene blue is a potent inhibitor of monoamine oxidase A (Ramsay et al., British Journal of Pharmacology, 2007), and a systematic review of case reports linked it with serotonin syndrome in patients taking serotonin reuptake inhibitors (Ng and Cameron, Psychosomatics, 2010). People with G6PD deficiency are also at risk from it. Add the lack of long-term trials in healthy adults, and a careful doctor will want to know your full medicine list before saying yes.

Who Should Not Take Methylene Blue Gummies

Serotonergic supplements such as St John’s wort, 5-HTP and tryptophan belong on the same avoid list. A gummy is easy to take casually, so keep to the label serving and do not stack two brands. Our guides to who should not take methylene blue, methylene blue interactions and methylene blue gummy side effects cover the details. Store gummies in a cool, dry place, and see our methylene blue shelf life guide for how long they keep.

How We Compared These Gummies

NooBlue makes Methylene Blue Gummies. They are our pick, and every figure for the other seven products is taken from their own product pages and Amazon listings, read in September 2026. We ranked our gummy first. The other seven are in order of cost per milligram of stated methylene blue, lowest first, with Neuropoise last because its page does not state a dose. The lab-document column sits apart from the ranking so you can weigh proof against price yourself.

• Dose and price: milligrams per gummy and serving size from each label, and price per milligram worked out from the listed price, never estimated.
• Lab documents: we opened every certificate shown on a product page and recorded the lab, sample, lot, dates and tests. Where a brand only claims testing, we say so.
• Ingredients and safety text: sugar, co-ingredients and whether the page names serotonergic medicines, G6PD deficiency and pregnancy.

We did not lab-test any competitor product, and we left out gummies we could not buy or verify this month, such as products that were sold out or had no live listing. If you are shopping by format rather than brand, our comparisons of methylene blue gummies vs capsules, gummies vs liquid and tablets vs liquid set out the trade-offs.

The Verdict

For most people, NooBlue Methylene Blue Gummies are the gummy to buy: a stated 10 mg with 25 mg of vitamin C, 0 g sugar, no blue mouth, full safety warnings on the product page, and a certificate you can match to a lot number. At $49.99 for a 60-day supply it is not the cheapest per milligram.

If cost per milligram is all that matters, MaxLife Naturals is lowest at its Amazon price, and Holistic MD is lowest per gummy when a seller offer is live. If you want a certificate that names the finished gummy, TrueHealthic has one, but ask about the lot first. If this is your first methylene blue product of any kind, a smaller fixed dose such as our 5 mg capsules is an easier start.

Methylene Blue Gummies Review: FAQ

What is the best methylene blue gummy on the market?

Our pick is NooBlue Methylene Blue Gummies: 10 mg of methylene blue with 25 mg of vitamin C per gummy, 0 g sugar, no blue mouth, and a linked ingredient certificate with a lot number. MaxLife Naturals is the cheapest per milligram at its Amazon price, and Holistic MD is the cheapest per gummy when a seller offer is live.

Do methylene blue gummies really work?

No trial has tested a methylene blue gummy. A small randomized study gave 26 adults either placebo or a single 280 mg dose and found about 7% more correct memory-retrieval answers an hour later. That dose is far higher than any gummy, so the evidence supports the mechanism more than any specific daily product.

Why do I feel so good on methylene blue?

Nobody can say for certain from one person’s experience. Methylene blue supports mitochondrial energy in lab studies, but at gummy doses there is no trial showing a felt effect, and expectation, sleep and a new morning routine all play a part. If you feel unusually wired or unwell, stop and talk to your doctor.

Why don’t doctors recommend methylene blue?

Mostly because of interactions. Methylene blue inhibits monoamine oxidase A and has been linked with serotonin syndrome in people taking serotonergic antidepressants. It is also unsafe with G6PD deficiency, and there are no long-term trials of daily supplement use in healthy adults.

Do methylene blue gummies turn your tongue blue?

Oxidized methylene blue is a strong blue dye, so drops can stain the mouth and tongue. NooBlue gummies don’t leave a blue mouth or tongue. With any format, your urine may turn blue or green, which is expected.

How much methylene blue is in a gummy?

In this review the stated doses run from 5 mg to 12 mg per gummy. NooBlue uses 10 mg. Blissta’s serving is two 7 mg gummies, and Neuropoise does not state a dose on its product page.

Which methylene blue gummy brands publish a certificate of analysis?

Three of the eight product pages show one: NooBlue (a CTLA report on the methylene blue ingredient lot), TrueHealthic (a ClearCert certificate naming the gummy, whose lot number also appears on its drops certificate) and Blue Organics (a 2024 heavy-metal and microbe report on a powder). Blissta says its certificate is published, but we found none on the page.

Can you take methylene blue gummies every day?

Daily use at label servings is common, but there is no long-term trial of daily use in healthy adults. Stick to one serving, and do not take it at all if you use serotonergic medicines, have G6PD deficiency, are pregnant or breastfeeding, or are under 18.

Do methylene blue gummies interact with other supplements?

Yes, with serotonergic ones. Avoid St John’s wort, 5-HTP and tryptophan alongside methylene blue, as well as SSRIs, SNRIs and MAOIs. Check anything else you take with your doctor or pharmacist.

Where can you buy methylene blue gummies?

Most brands here sell through Amazon or their own stores. NooBlue sells direct from its own store with free worldwide shipping on orders $100+, 30-day returns and dispatch in 1–2 business days with tracking. Our guide to finding methylene blue in stores and pharmacies covers other options.

More Methylene Blue Buying Guides

• Best methylene blue gummies compared
• Best methylene blue capsules
• Best methylene blue supplements
• Top methylene blue brands
• Methylene blue for beginners
• Shop all NooBlue formats

Sources

1. NooBlue. Methylene Blue Gummies product page, supplement facts and CTLA certificate (report 135621, lot 2025022801). nooblue.com (read September 2026).
2. MaxLife Naturals. Liposomal Pure Methylene Blue Gummies, Amazon listing B0FKC58S39 and brand store page (read September 2026).
3. Holistic MD. Methylene Blue for Humans gummies, Amazon listing B0F322H18D (read September 2026).
4. Blissta. Ultra Blue Gummies product page (read September 2026).
5. Inditropic. Methylene Blue Gummies, Amazon listing B0GQGCYYPG (read September 2026).
6. TrueHealthic. Methylene Blue Gummies product page and ClearCert certificate; TrueHealthic 1% drops page and its ClearCert certificate (read September 2026).
7. Blue Organics. Methylene Blue Gummies product page and Nexora Labs report (read September 2026).
8. Neuropoise. Methylene Blue Gummies product page (read September 2026).
9. Atamna H, Nguyen A, Schultz C, et al. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB Journal. 2008;22(3):703-712. PubMed 17928358
10. Rodriguez P, Zhou W, Barrett DW, et al. Multimodal randomized functional MR imaging of the effects of methylene blue in the human brain. Radiology. 2016;281(2):516-526. PubMed 27351678
11. Rodriguez P, Singh AP, Malloy KE, et al. Methylene blue modulates functional connectivity in the human brain. Brain Imaging and Behavior. 2017;11(3):640-648. PubMed 26961091
12. Rojas JC, Bruchey AK, Gonzalez-Lima F. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Progress in Neurobiology. 2012;96(1):32-45. PubMed 22067440
13. Ramsay RR, Dunford C, Gillman PK. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. British Journal of Pharmacology. 2007;152(6):946-951. PubMed 17721552
14. Ng BK, Cameron AJ. The role of methylene blue in serotonin syndrome: a systematic review. Psychosomatics. 2010;51(3):194-200. PubMed 20484716

This article is for educational purposes only and is not medical advice. Talk to your doctor before starting methylene blue, especially if you take any prescription medicine. Competitor listings and prices were read in September 2026 and can change.