By NooBlue Editorial · About our editorial standards
Key takeaways
- MitoZen’s methylene blue product is Lumetol Blue Bars: 40 mg or 180 mg of USP-grade methylene blue per bar, with vitamin C and a proprietary blend of polyphenols, oils, terpenes and a probiotic.
- MitoZen’s own serving is a quarter to a full 40 mg bar (about 10 to 40 mg) or a quarter to a half 180 mg bar (about 45 to 90 mg). That is many times a 5 mg capsule or a 10 mg gummy.
- A 40 mg pack is $89.95 and a 180 mg pack is $179.95, but the page does not say how many bars come in a pack, so a fair cost per milligram cannot be worked out from it.
- The page shows no certificate of analysis, the blend has no amounts, and the bars need refrigeration and use within six months.
- For a low, repeatable daily dose, our pick is NooBlue: 5 mg capsules, 10 mg gummies or 1% drops at 0.5 mg per drop. Methylene blue is not for anyone taking serotonergic medicines, anyone with G6PD deficiency, anyone pregnant or breastfeeding, or anyone under 18.
Short answer: MitoZen methylene blue is a high-dose, multi-ingredient bar built for people who want tens of milligrams at a time alongside a light-therapy routine. The methylene blue content is clearly stated, but the rest of the formula is a blend with no amounts, no lab document is shown, and the pack size is not stated. For a low daily dose you can measure exactly, NooBlue is our pick.
This MitoZen methylene blue review covers what the Lumetol Blue Bars contain, what a serving delivers, what the packs cost, how open the brand is about testing, and who the format suits. NooBlue makes methylene blue capsules, gummies and drops. They are our pick for a daily routine, and every MitoZen figure here is taken from MitoZen’s own product page, read in September 2026. For the wider field, see our comparison of the best methylene blue supplements and our overview of the top methylene blue brands.
What MitoZen Methylene Blue Actually Is
MitoZen sells a wide range of supplements in unusual formats, including suppository “Bullets”, liposomal liquids, oral tinctures and bars. Its oral methylene blue product is Lumetol Blue Bars. MitoZen says plainly that they are not troches: you place a piece at the back of your mouth and wash it down with liquid to avoid blue staining.
What is in a bar. The supplement facts list methylene blue “USP Grade (pharmaceutical grade)” at 40 mg or 180 mg, then a “Proprietary Blend of Photosensitive Polyphenols” with no individual amounts: phycocyanin, EGCG, lutein, quercetin, curcumin and riboflavin, boswellia and copaiba essential oils, a terpene profile, vitamin C, organic palm oil, an SRT polysaccharide complex and a probiotic blend.
How it is stored. The page says to keep the bars refrigerated and out of direct sunlight and to use them within 6 months of purchase. The pack label in the product photos reads “Professional use only” and “Store in refrigerated climate”.
Other blue products. MitoZen also lists Blue Eyes Drops (5 ml, $79.95 regular or $99.95 gold), Blue Ears Drops ($79.95) and a blue cream. Those are topical products and are not interchangeable with an oral supplement, so this review sticks to the bars. For a very different approach to the same compound, read our Meraki methylene blue review, which covers a plain 0.5% liquid.
Lumetol Blue Dose: 40 mg, 180 mg and What a Serving Means
MitoZen’s stated servings are a quarter to a full bar of the 40 mg version, which the brand puts at about 10 to 40 mg of methylene blue, and a quarter to a half bar of the 180 mg version, about 45 to 90 mg.
Set that against a measured daily product. A NooBlue capsule holds 5 mg and a NooBlue gummy holds 10 mg. The smallest 40 mg serving, about 10 mg, matches one gummy. A 180 mg serving of 45 to 90 mg is 9 to 18 times one capsule, from a bar you break by hand.
More is not automatically better with methylene blue. In a rat study, 4 mg/kg improved object memory, 1 to 10 mg/kg left running and feeding unchanged, and 50 to 100 mg/kg reduced wheel running (Riha et al., European Journal of Pharmacology, 2005). A review by Rojas, Bruchey and Gonzalez-Lima (2012) describes this dose-dependent pattern and the electron-cycling mechanism behind it. In people, the best-known study gave 13 healthy adults a single 280 mg oral dose, about 4 mg/kg, and found about a 7% increase in correct memory-retrieval responses an hour later (Rodriguez et al., Radiology, 2016). That was one dose under study conditions, not a daily routine.
The practical point is not that MitoZen’s dosing is wrong. It is that a hand-broken bar is a blunt tool for landing on a specific number of milligrams, and the numbers are large. If you are working out how many mg of methylene blue per day suits you, a fixed 5 mg capsule or a drop you can count gets you there with less guesswork. We compare those two in NooBlue capsules vs liquid solutions.
MitoZen’s page tells buyers not to combine the bars with SSRIs or other serotonin-boosting medicines, or with MDMA, MDA, ayahuasca, psilocybin or any compound with MAO-inhibiting or serotonergic activity. It also argues that some health bodies have softened their warning. We would not lean on that: methylene blue is a potent inhibitor of monoamine oxidase A (Ramsay et al., 2007), and a systematic review linked it with serotonin syndrome in patients on serotonin reuptake inhibitors (Ng and Cameron, 2010). The page asks pregnant or breastfeeding buyers and those on medicines to consult a professional, and says the product is not for under-18s. We found no G6PD warning on it.
MitoZen Price: What a Pack Costs
These are the Lumetol Blue prices on MitoZen’s store as of Sep 2026:
| Option | Price | Listed compare-at price |
|---|---|---|
| 40 mg, 1 pack | $89.95 | $109.95 |
| 40 mg, 3 packs | $269.85 | $299.95 |
| 180 mg, 1 pack | $179.95 | None listed |
| 180 mg, 3 packs | $399.97 | None listed |
The missing number is how many bars are in a pack. The page does not say, and the product photo shows a divided tray rather than a single bar. Without a bar count, the cost per milligram of methylene blue cannot be worked out honestly, so we have not published one. An earlier version of this review treated one pack as one bar, which is not supported by the page. If you are comparing value, ask MitoZen for the bar count before you buy.
For reference, NooBlue’s prices are fixed per milligram. The methylene blue capsules are $37.99 for 60 x 5 mg, or $0.63 a capsule. The methylene blue gummies are $49.99 for 60 x 10 mg, or $0.83 a gummy. The 1% methylene blue drops are $29.99 for 50 ml, about 100 servings of 5 mg at $0.30 each. Our guide to the price range of quality methylene blue supplements puts those figures in context.
Formula Transparency and Testing
Two things matter when you buy a compound like this: knowing what is in it, and having a document that confirms the label.
On the first, MitoZen states the methylene blue clearly, 40 mg or 180 mg per bar, as USP grade. Everything else sits inside the proprietary blend with no amounts and “Daily Value not established”. That is common in supplements, but it means you cannot judge the supporting ingredients or price them.
On the second, we found no certificate of analysis on the Lumetol Blue page. That does not mean anything is wrong with the product. It does mean the purity claim rests on the brand’s word. Our guides on how to check a methylene blue supplement is authentic and how to read a certificate of analysis cover what to ask for.
For comparison, NooBlue links a Contract Testing Laboratories of America (CTLA) report on every product page. It covers the methylene blue ingredient lot, with an HPLC identity result of “Conforms” and results for arsenic, cadmium, mercury and lead. It is an ingredient-level report: it gives no purity percentage and does not test each finished batch, and the product pages say so. The same question of what a brand will show you came up in our TrueHealthic gummies review and our methylene blue gummies review, where we read every certificate the brands publish.
MitoZen vs NooBlue at a Glance
| MitoZen Lumetol Blue Bars | NooBlue (capsules, gummies, drops) | |
|---|---|---|
| Methylene blue per unit | 40 mg or 180 mg per bar | 5 mg capsule, 10 mg gummy, 0.5 mg per drop |
| Brand’s serving | About 10 to 40 mg or 45 to 90 mg, broken by hand | One capsule or one gummy a day. Drops measured by the drop |
| Other ingredients | Proprietary blend, no amounts | Capsules: 10 mg vitamin C. Gummies: 25 mg vitamin C, 0 g sugar |
| Storage | Refrigerate, use within 6 months | Cool, dry place |
| Blue mouth | Wash down with liquid to avoid staining | Capsules are swallowed. Gummies don’t leave a blue mouth. Drops can stain |
| Lab document on the page | None found | CTLA ingredient report, identity and four heavy metals |
| Price | $89.95 to $179.95 a pack, bar count not stated | $29.99 to $49.99 a bottle |
| Safety text on the page | Serotonergic medicines, pregnancy, under 18. No G6PD line found | Serotonergic medicines, G6PD deficiency, pregnancy and breastfeeding, under 18 |
Who MitoZen Lumetol Blue Suits, and Who It Doesn’t
MitoZen Lumetol Blue 180 mg fits someone who has already decided, with their doctor, that they want doses in the tens of milligrams, wants the polyphenol blend, and is happy to refrigerate and break a bar by hand.
MitoZen Lumetol Blue 40 mg is the lower-commitment way to try the bar format, with servings starting around 10 mg.
For a low, repeatable daily dose, our pick is NooBlue. The 5 mg capsules are the simplest start: one a day, nothing to measure. The 10 mg gummies suit people who would rather chew than swallow, with 25 mg of vitamin C, 0 g sugar and no blue mouth. The 1% drops give the finest control, 0.5 mg at a time, at the lowest cost per serving of the three.
Whichever you choose, start low and know exactly how many milligrams you are taking. Our guide to methylene blue side effects covers what to watch for, and does methylene blue work? sets out what the human trials do and don’t show.
The “Red, Blue, O2” Angle: Why MitoZen Pairs Methylene Blue With Light
MitoZen builds its range around light and oxygen routines, and the Lumetol Blue label tells you to use the bar before light exposure and says it can be used with red light therapy. The biology behind the pairing is real: red and near-infrared light and low-dose methylene blue both act on cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain. In cultured human cells, nanomolar methylene blue raised complex IV activity by 30% and oxygen consumption by 37% to 70% (Atamna et al., 2008).
The dose caveat matters more here than usual. Under strong light, methylene blue is a photosensitizer that can generate reactive oxygen species, which is the opposite of what people using it for energy want. A serving of 45 to 90 mg is far from the low doses most home light routines are built around. Our guide to methylene blue and red light therapy covers how people combine them, and our explainer on how methylene blue works walks through the pathway.
Who Should Not Take Methylene Blue
- Do not take methylene blue with SSRIs, SNRIs, MAOIs or other serotonergic medicines, including many antidepressants. The combination can cause serotonin syndrome.
- Do not take it if you have G6PD deficiency.
- Do not take it if you are pregnant or breastfeeding.
- Not for anyone under 18.
- Methylene blue can turn urine blue or green. This is expected.
- Talk to your doctor before you start if you take any prescription medicine.
Higher doses make these points more important, not less. If you have a liver or kidney condition, see our note on methylene blue and liver safety and talk to your doctor first.
The Verdict on MitoZen Methylene Blue
MitoZen Lumetol Blue is a considered product for a narrow buyer: someone who wants high single doses, a polyphenol blend and a light-therapy routine, and who will refrigerate a bar and break it by hand. The methylene blue content is clear. The rest of the formula, the pack size and the lab testing are not shown on the page, so you are buying partly on trust.
For most people, a low daily dose you can measure exactly is the better starting point. That is why our pick is NooBlue: 5 mg capsules, 10 mg gummies or 1% drops, each with a linked ingredient lab report and the full safety list on the product page. For more brand-by-brand verdicts, see our methylene blue reviews, our Troscriptions review and our Blissta review.
MitoZen Methylene Blue: Frequently Asked Questions
How much methylene blue is in a Lumetol Blue bar?
MitoZen sells Lumetol Blue Bars in two strengths, 40 mg and 180 mg of methylene blue per bar. Its suggested serving is a quarter to a full 40 mg bar, about 10 to 40 mg, or a quarter to a half 180 mg bar, about 45 to 90 mg.
How many bars are in a MitoZen Lumetol Blue pack?
The product page does not say. It lists prices per pack, $89.95 for 40 mg and $179.95 for 180 mg, and the photo shows a divided tray. Ask MitoZen for the bar count before you compare cost per milligram.
Is MitoZen methylene blue worth the price?
It depends on what you want. If you want the bar format, high single doses and the polyphenol blend, it is one of very few products like it. If you want a low daily dose of methylene blue with a stated amount of everything in it, a 5 mg capsule, 10 mg gummy or measured drop fits that goal better.
Is it safe to take methylene blue daily?
Low doses are commonly taken daily, but there are no long-term trials of daily supplement use in healthy adults. Start low, stay at the label serving, and do not take it at all if you use serotonergic medicines, have G6PD deficiency, are pregnant or breastfeeding, or are under 18.
What drugs should not be taken with methylene blue?
SSRIs, SNRIs, MAOIs and other serotonergic medicines, including many antidepressants, because the combination can cause serotonin syndrome. Serotonergic supplements such as St John’s wort, 5-HTP and tryptophan belong on the same list. If you take any prescription medicine, check with your doctor or pharmacist first.
Does MitoZen make methylene blue eye drops?
MitoZen lists Blue Eyes Drops in 5 ml bottles at $79.95 (regular) or $99.95 (gold), and Blue Ears Drops at $79.95. They are separate topical products and are not a substitute for an oral supplement.
What is MitoZen methylene blue used for?
MitoZen positions Lumetol Blue as a mitochondrial and cellular-energy supplement to use with light therapy, and its marketing mentions focus and vitality. People take methylene blue across brands because it can act as an electron carrier in the mitochondria, which supports cellular energy. What sets MitoZen apart is the high serving size and the added blend.
What does methylene blue do for your mitochondria?
At low concentrations methylene blue can accept electrons and pass them to cytochrome c oxidase, which supports ATP production in the mitochondria. In cultured human cells it raised complex IV activity by 30%. At higher concentrations the same molecule can add to oxidative stress instead, which is why the research keeps pointing to low doses.
Sources
- MitoZen. Lumetol Blue Bars product page and supplement facts; Blue Eyes Drops and Blue Ears Drops listings. mitozen.com (read September 2026).
- Riha PD, Bruchey AK, Echevarria DJ, Gonzalez-Lima F. Memory facilitation by methylene blue: dose-dependent effect on behavior and brain oxygen consumption. European Journal of Pharmacology. 2005;511(2-3):151-158. PubMed 15792783
- Rojas JC, Bruchey AK, Gonzalez-Lima F. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Progress in Neurobiology. 2012;96(1):32-45. PubMed 22067440
- Rodriguez P, Zhou W, Barrett DW, et al. Multimodal randomized functional MR imaging of the effects of methylene blue in the human brain. Radiology. 2016;281(2):516-526. PubMed 27351678
- Atamna H, Nguyen A, Schultz C, et al. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB Journal. 2008;22(3):703-712. PubMed 17928358
- Ramsay RR, Dunford C, Gillman PK. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. British Journal of Pharmacology. 2007;152(6):946-951. PubMed 17721552
- Ng BK, Cameron AJ. The role of methylene blue in serotonin syndrome: a systematic review. Psychosomatics. 2010;51(3):194-200. PubMed 20484716
This article is for educational purposes only and is not medical advice. Talk to your doctor before starting methylene blue, especially if you take any prescription medicine. MitoZen prices and label details were read in September 2026 and can change.
